Reel drag or line releases?
Dipseys, downrigger releases and planer board releases should be set on the water under the conditions that you are fishing in. Wind, waves, boat speed and lure types all play part in the process. The first time usually take the longest to set up. You'll want your releases to trigger when a fish hits and not until. Adjust the tension so your line barely stays in the clamp.
Fireline and other superlines require more tension than mono because they're slicker. Try giving your fireline a twist or loop or double it up at the release if they still let go early.
Your best chance of landing the next world record requires a totally smooooooth reel drag. Drag should be set while the reel is on the rod. Stiff rods need less drag and limber rod could get away with more.
No stuccato vibrations of any kind. Nice and smooth. A jerky drag puts too much strain on any kind of fishing line and it will pop. While there is no substitute for an eighty yard run (checks drag under heated conditions), you can have the line pulled from the rod tip and check for that stuccato feel or sound. Have a buddy pull the line out from the rod tip or tie your line to a post and give the rod a continuous pull. If you feel any stop and go vibration, the reel needs to be checked.
p.s. "Bob Hicks", will you kindly delete the prior "Anonymous" post. I must be to poor to pay attention. Thanx.